Indole alkaloids from "hairy roots" of Rauwolfia serpentina
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چکیده
منابع مشابه
Docking Studies of Rauwolfia Serpentina Alkaloids as Insulin Receptor Activators
Rauwolfia serpentina also known as Sarpagandha is an integral part of Ayurvedic medical system for over centuries for the treatment of various ailments. The leaves and roots of Rauwolfia serpentina contain alkaloids which are secondary metabolites. Major alkaloids identified are Reserpine, Rauwolfine, Serpentine, Sarpagine, Ajmaline, Yohimbine and Ajmalicine. Insulin binds to insulin receptors ...
متن کاملAnalysis of Indole Alkaloids from Rhazya stricta Hairy Roots by Ultra-Performance Liquid Chromatography-Mass Spectrometry.
Rhazya stricta Decne. (Apocynaceae) contains a large number of terpenoid indole alkaloids (TIAs). This study focused on the composition of alkaloids obtained from transformed hairy root cultures of R. stricta employing ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). In the UPLC-MS analyses, a total of 20 TIAs were identified from crude extracts. Eburenine and vincanine were...
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BACKGROUND The antihypertensive reserpine is an indole alkaloid from Rauwolfia serpentina and exerts also profound activity against cancer cells in vitro and in vivo. The present investigation was undertaken to investigate possible modes of action to explain its activity toward drug-resistant tumor cells. MATERIAL AND METHODS Sensitive and drug-resistant tumor cell lines overexpressing P-glyc...
متن کاملRauwolfia Serpentina in Essential Hypertension
jHauwolfia serpentina has been known as a medicinal plant in India for a long time but its use in the treatment of hypertension is of comparatively recent origin. The dried root contains 1 per cent of total alkaloids besides resin, starch, potassium carbonate, phosphate, silicate and traces of iron and manganese (Sen and Bose, 1931). Siddiqui and Siddiqui (1931) found two groups of alkaloids an...
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The therapeutic problem of satisfactorily controlling acute and chronic states of psychomotor excitement is an ever-present one confronting psychiatrists engaged in hospital practice. Admittedly, the application of current methods of treatment, such as systematic pharmacological sedation by means of barbiturates and other drugs or electroconvulsive therapy, will in most cases control excited be...
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ژورنال
عنوان ژورنال: Canadian Journal of Chemistry
سال: 1993
ISSN: 0008-4042,1480-3291
DOI: 10.1139/v93-276